"Bono has been an inspiration to many people around the world through his music and humanitarian efforts," said Bond. "We are delighted to honor him with this award in recognition of the difference he has made, and to acknowledge his ongoing campaigning to actively engage Americans from all walks of life in the fight against extreme poverty and the global AIDS pandemic."

Hosted by LL Cool J

Presented by Julian Bond, Tyra Banks and Chris Tucker

Tribute medley of "Sunday Bloody Sunday" and "Pride" by The Roots

Bono gives a rousing speech at the end, prompting a standing ovation from the adoring crowd.